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Microfluidic Gas‐Flow Imaging Utilizing Parahydrogen‐Induced Polarization and Remote‐Detection NMR
Author(s) -
Telkki VilleVeikko,
Zhivonitko Vladimir V.,
Ahola Susanna,
Kovtunov Kirill V.,
Jokisaari Jukka,
Koptyug Igor V.
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201002685
Subject(s) - spin isomers of hydrogen , microfluidics , image resolution , polarization (electrochemistry) , hyperpolarization (physics) , materials science , visualization , flow (mathematics) , analytical chemistry (journal) , nanotechnology , chemistry , nuclear magnetic resonance , nuclear magnetic resonance spectroscopy , optics , computer science , chromatography , physics , hydrogen , data mining , organic chemistry , mechanics
Sensitivity enhancement of several orders of magnitude provided by combining parahydrogen‐induced polarization (PHIP) and remote‐detection (RD) NMR techniques enables gas‐flow visualization in microfluidic devices (see scheme). A 7700‐fold reduction in the imaging time compared to the current state‐of‐the‐art is achieved, and it can also be used to significantly improve the spatial resolution in such experiments.