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Chiral Brønsted Acid Catalyzed Enantioselective α‐Aminoxylation of Enecarbamates
Author(s) -
Lu Min,
Lu Yunpeng,
Zhu Di,
Zeng Xiaofei,
Li Xinsheng,
Zhong Guofu
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201002640
Subject(s) - enantioselective synthesis , scope (computer science) , catalysis , brønsted–lowry acid–base theory , substrate (aquarium) , stereoselectivity , chemistry , simple (philosophy) , combinatorial chemistry , computer science , organic chemistry , stereochemistry , philosophy , programming language , biology , epistemology , ecology
A practically simple , highly enantioselective Brønsted acid catalyzed α‐aminoxylation of enecarbamates extends the substrate scope for the α‐aminoxylation to linear and aromatic ketones, allowing convergent and stereoselective access to valuable α‐hydroxy ketones, β‐amino alcohols, and cis ‐oxazolidinones.