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Deconstruction as a Strategy for the Design of Libraries of Self‐Assembling Dendrons
Author(s) -
Rosen Brad M.,
Peterca Mihai,
Huang Chenghong,
Zeng Xiangbing,
Ungar Goran,
Percec Virgil
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201002514
Subject(s) - dendrimer , deconstruction (building) , rational design , nanotechnology , computer science , materials science , engineering , polymer chemistry , waste management
Bringing down the dendron : The deconstruction of self‐assembling dendrons represents a new strategy for the rational design of libraries of self‐assembling dendrons with unprecedented primary structure (see picture). In this strategy, molecular targets are designed by systematically removing branches from a parent dendron. This approach provides a diversity of molecular topologies unencountered in the generational synthesis of dendrons.