Radiosynthesis and Evaluation of [ 18 F]Selectfluor bis(triflate) | Zendy

Teare Harriet | Zendy; Robins Edward G. | Zendy; Kirjavainen Anna | Zendy; Forsback Sarita | Zendy; Sandford Graham | Zendy; Solin Olof | Zendy; Luthra Sajinder K. | Zendy; Gouverneur Véronique | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Radiosynthesis and Evaluation of [ 18 F]Selectfluor bis(triflate)

Author(s) -

Teare Harriet,

Robins Edward G.,

Kirjavainen Anna,

Forsback Sarita,

Sandford Graham,

Solin Olof,

Luthra Sajinder K.,

Gouverneur Véronique

Publication year - 2010

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201002310

Subject(s) - selectfluor , trifluoromethanesulfonate , reagent , electrophile , chemistry , combinatorial chemistry , organic chemistry , catalysis

Selectfluor, one of the most reactive and commonly used electrophilic fluorinating N–F reagents, has been radiolabeled with 18 F. The resulting new [ 18 F]‐labeled N–F reagent is safe, nontoxic, and easy to handle. The combined use of [ 18 F]Selectfluor bis(triflate) and AgOTf allows for the preparation of electron‐rich 18 F‐aromatic compounds through a simple “shake and mix” protocol at room temperature (see scheme; SA=specific activtiy).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research