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Inside Cover: Facile, Template‐Free Synthesis of Stimuli‐Responsive Polymer Nanocapsules for Targeted Drug Delivery (Angew. Chem. Int. Ed. 26/2010)
Author(s) -
Kim Eunju,
Kim Dongwoo,
Jung Hyuntae,
Lee Jiyeong,
Paul Somak,
Selvapalam Narayanan,
Yang Yosep,
Lim Namseok,
Park Chan Gyung,
Kim Kimoon
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201002201
Subject(s) - nanocapsules , polymer , drug delivery , nanotechnology , disulfide bond , combinatorial chemistry , targeted drug delivery , chemistry , materials science , biophysics , nanoparticle , organic chemistry , biochemistry , biology
Open Sesame! A template‐free synthetic approach to stimuli‐responsive polymer nanocapsules that are potentially useful for targeted drug delivery has been developed. In their Communication on p. 4405 ff. , K. Kim and co‐workers show that reductively labile polymer nanocapsules composed of CB[6] and disulfide bridges allow not only facile, noncovalent surface modification for targeted delivery but also the release of encapsulated cargo in response to a predefined redox stimulus in an intracellular environment.