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One‐Pot Synthesis of Menthol Catalyzed by a Highly Diastereoselective Au/MgF 2 Catalyst
Author(s) -
Negoi Alina,
Wuttke Stefan,
Kemnitz Erhard,
Macovei Dan,
Parvulescu Vasile I.,
Teodorescu C. M.,
Coman Simona M.
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201002090
Subject(s) - catalysis , menthol , chemistry , combinatorial chemistry , organic chemistry
No toxic compounds such as KCN and no thermal activation is required for the preparation of Au/MgF 2 complexes by a simple and facile “incipient wetness impregnation” method in which hydrogen tetrachloroaurate (HAuCl 4 ) is the gold precursor. One of the complexes prepared exhibits unique catalytic properties and serves as a heterogeneous catalyst for the highly diastereoselective one‐pot synthesis of (±)‐menthol from citronellal (see picture).