Constructing Multiply Substituted Arenes Using Sequential Palladium(II)‐Catalyzed CH Olefination | Zendy

Engle Keary M. | Zendy; Wang DongHui | Zendy; Yu JinQuan | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Constructing Multiply Substituted Arenes Using Sequential Palladium(II)‐Catalyzed CH Olefination

Author(s) -

Engle Keary M.,

Wang DongHui,

Yu JinQuan

Publication year - 2010

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201002077

Subject(s) - palladium , catalysis , reactivity (psychology) , selectivity , chemistry , combinatorial chemistry , surface modification , functional group , medicinal chemistry , stereochemistry , organic chemistry , medicine , alternative medicine , pathology , polymer

A balancing act : Complementary catalytic systems are described, in which the reactivity/selectivity balance in Pd II ‐catalyzed ortho ‐CH olefination can be modulated to enable sequential CH functionalization for the rapid preparation of 1,2,3‐trisubstituted arenes 1 . Additionally, a rare example of iterative CH activation, in which a newly installed functional group directs subsequent CH activation has been demonstrated ( 2 ).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research