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Vitamin B 12 Mimics Having a Peptide Backbone and Tuneable Coordination and Redox Properties
Author(s) -
Zhou Kai,
Zelder Felix
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201001928
Subject(s) - linker , corrin , vitamin b12 , peptide , chemistry , combinatorial chemistry , redox , computer science , stereochemistry , biochemistry , organic chemistry , operating system
A fortified vitamin : A new class of vitamin B 12 mimics with a peptide backbone has been developed (see structure). The choice of an appropriate linker between the corrin macrocycle and the dimethylbenzimidazole base makes it possible to modulate selectively the coordination and redox properties at the metal center.