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Asymmetric Amplification in Phosphoric Acid Catalyzed Reactions
Author(s) -
Li Nan,
Chen XiaoHua,
Zhou ShiMing,
Luo ShiWei,
Song Jin,
Ren Lei,
Gong LiuZhu
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201001723
Subject(s) - phosphoric acid , enantioselective synthesis , catalysis , chemistry , supramolecular chemistry , hydrogen bond , molecule , optically active , organic chemistry , combinatorial chemistry
An ee amp : Asymmetric amplification in reactions catalyzed by phosphoric acids arose from the formation of less soluble supramolecular structures (see scheme; O red, P yellow, C gray, H white) of the racemic phosphoric acids that participate in hydrogen bonds with the crystalline water molecules. The finding shows that highly enantioselective reactions can be observed by using non‐optically pure phosphoric acids.