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Cover Picture: Highly Active Chiral Ruthenium‐Based Metathesis Catalysts through a Monosubstitution in the N‐Heterocyclic Carbene (Angew. Chem. Int. Ed. 23/2010)
Author(s) -
Tiede Sascha,
Berger Anke,
Schlesiger David,
Rost Daniel,
Lühl Anja,
Blechert Siegfried
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201001706
Subject(s) - ruthenium , metathesis , catalysis , carbene , chemistry , ligand (biochemistry) , selectivity , combinatorial chemistry , ring (chemistry) , stereochemistry , medicinal chemistry , organic chemistry , polymerization , receptor , polymer , biochemistry
One handed is very efficient not only for fiddler crabs, but also for chiral ruthenium metathesis (pre)catalysts that contain a monosubstituted carbon center in the N‐heterocyclic ligand. In their Communication on page 3972 ff. S. Blechert and co‐workers show that through the combination of ligands a highly stable catalyst is formed that rapidly initiates the asymmetric ring‐opening cross‐metathesis and delivers high E ‐isomer selectivity and high enantioselectivity. (Photo: Thorsten Stegmann.)