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Quantitative CARS Molecular Fingerprinting of Single Living Cells with the Use of the Maximum Entropy Method
Author(s) -
Okuno Masanari,
Kano Hideaki,
Leproux Philippe,
Couderc Vincent,
Day James P. R.,
Bonn Mischa,
Hamaguchi Hiroo
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201001560
Subject(s) - raman microspectroscopy , raman scattering , raman spectroscopy , principle of maximum entropy , microscopy , entropy (arrow of time) , biological system , biophysics , chemistry , materials science , analytical chemistry (journal) , optics , physics , biology , computer science , chromatography , artificial intelligence , thermodynamics
Fast CARS : The cell‐death process was observed in real time at the subcellular level by coherent anti‐Stokes Raman microspectroscopy, an extension of anti‐Stokes Raman scattering (CARS) microscopy. Changes in the chemical contrast during the dying process can be clearly resolved (see picture).