Premium
Discrimination of Human Astrocytoma Subtypes by Lipid Analysis Using Desorption Electrospray Ionization Imaging Mass Spectrometry
Author(s) -
Eberlin Livia S.,
Dill Allison L.,
Golby Alexandra J.,
Ligon Keith L.,
Wiseman Justin M.,
Cooks R. Graham,
Agar Nathalie Y. R.
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201001452
Subject(s) - mass spectrometry , electrospray ionization , electrospray , chemistry , desorption , desorption electrospray ionization , ionization , analytical chemistry (journal) , chromatography , chemical ionization , ion , organic chemistry , adsorption
Differentiation of human brain astrocytic tumor grades can be achieved by direct lipid analysis using desorption electrospray ionization mass spectrometry (DESI‐MS). Distinctive lipid profiles are associated with the degree of malignancy, grades II, III, and IV (see picture).