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A Graphene Oxide Based Immuno‐biosensor for Pathogen Detection
Author(s) -
Jung Jae Hwan,
Cheon Doo Sung,
Liu Fei,
Lee Kang Bum,
Seo Tae Seok
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201001428
Subject(s) - graphene , förster resonance energy transfer , biosensor , oxide , fluorescence , photoluminescence , nanotechnology , quenching (fluorescence) , energy transfer , materials science , chemistry , optoelectronics , optics , physics , molecular physics , metallurgy
Don′t FRET when I GO : Sensitive and selective rotavirus detection is achieved by using the photoluminescence of a graphene oxide (GO) array. The target cell was captured by the rotavirus‐specific antibody immobilized on the GO array, and the binding event was monitored by observing the fluorescence quenching that results from fluorescence resonance energy transfer (FRET) between GO and gold nanoparticles linked to the antibodies (see picture).