Self‐Assembly of Thermally Responsive Amphiphilic Diblock Copolypeptides into Spherical Micellar Nanoparticles | Zendy

Kim Wookhyun | Zendy; Thévenot Julie | Zendy; Ibarboure Emmanuel | Zendy; Lecommandoux Sébastien | Zendy; Chaikof Elliot L. | Zendy

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Self‐Assembly of Thermally Responsive Amphiphilic Diblock Copolypeptides into Spherical Micellar Nanoparticles

Author(s) -

Kim Wookhyun,

Thévenot Julie,

Ibarboure Emmanuel,

Lecommandoux Sébastien,

Chaikof Elliot L.

Publication year - 2010

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201001356

Subject(s) - amphiphile , micelle , nanoparticle , materials science , chemical engineering , self assembly , polymer chemistry , nanotechnology , copolymer , chemistry , composite material , organic chemistry , polymer , aqueous solution , engineering

Stable micellar structures were synthesized containing cysteine residues at the diblock interface to stabilize micellar structure (see picture). Self‐assembly of these copolypeptides affords a new class of protein nanoparticles with potential applications in drug‐delivery and bioimaging.

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