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Artificial Control of Cell Signaling and Growth by Magnetic Nanoparticles
Author(s) -
Lee JaeHyun,
Kim Eun Sook,
Cho Mi Hyeon,
Son Mina,
Yeon SooIn,
Shin JeonSoo,
Cheon Jinwoo
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201001149
Subject(s) - magnetic nanoparticles , microbiology and biotechnology , cell , receptor , nanotechnology , nanoparticle , control (management) , computer science , cell growth , signal transduction , cell signaling , chemistry , computational biology , biology , materials science , artificial intelligence , biochemistry
Magnetic attraction : Artificial control of cell activities is achieved by nanoscale magneto‐activated cellular signaling (N‐MACS), in which magnetic nanoparticles are selectively linked to cell surface receptors and aggregated by an external magnetic field. Such mechanocellular activation induces downstream cell signaling and initiates tubulogenesis in the preangiogenesis stage of endothelial cells (see picture).