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Facile Two‐Step Synthesis of Porous Antigen‐Loaded Degradable Polyelectrolyte Microspheres
Author(s) -
Dierendonck Marijke,
De Koker Stefaan,
Cuvelier Claude,
Grooten Johan,
Vervaet Chris,
Remon JeanPaul,
De Geest Bruno G.
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201001046
Subject(s) - polyelectrolyte , microsphere , chemical engineering , porosity , materials science , chemistry , polymer chemistry , polymer , composite material , engineering
Pore medicine : Porous antigen‐loaded degradable polyelectrolyte microspheres are produced in a straightforward way providing high encapsulation efficiencies and efficient internalization by antigen‐presenting cells. This system could find application as multilayer capsules in gene and drug delivery and for enzymatic microreactors.