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X‐Ray Structures of Copper(II) and Nickel(II) Radical Salen Complexes: The Preference of Galactose Oxidase for Copper(II)
Author(s) -
Orio Maylis,
Jarjayes Olivier,
Kanso Hussein,
Philouze Christian,
Neese Frank,
Thomas Fabrice
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201001040
Subject(s) - galactose oxidase , copper , nickel , chemistry , ligand (biochemistry) , reactivity (psychology) , ring (chemistry) , polymer chemistry , crystallography , metal , stereochemistry , photochemistry , galactose , organic chemistry , biochemistry , medicine , receptor , alternative medicine , pathology
Copper or nickel? The depicted Cu II salen complex, an active‐site model of galactose oxidase (GO), is a localized radical in the solid state with a quinoid distribution of bond lengths in one ring. While the ligand‐radical structure is not metal‐dependent, the composition of the radical SOMO is. This feature may explain the much lower reactivity of the Ni complex and nature's preference for a Cu II center in GO.