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Highly Active Chiral Ruthenium‐Based Metathesis Catalysts through a Monosubstitution in the N‐Heterocyclic Carbene
Author(s) -
Tiede Sascha,
Berger Anke,
Schlesiger David,
Rost Daniel,
Lühl Anja,
Blechert Siegfried
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201000940
Subject(s) - carbene , ruthenium , metathesis , catalysis , selectivity , combinatorial chemistry , chemistry , ligand (biochemistry) , carbon atom , ring (chemistry) , organic chemistry , polymerization , polymer , biochemistry , receptor
Single (substitution) is better : New chiral ruthenium metathesis (pre)catalysts with a monosubstituted carbon atom in the N‐heterocyclic carbene ligand are highly stable in solution, initiate easily, show very high enantioselectivity and excellent E selectivity in asymmetric ring‐opening cross‐metathesis (see scheme).