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Metal‐Free, Aerobic Dioxygenation of Alkenes Using Hydroxamic Acids
Author(s) -
Schmidt Valerie A.,
Alexanian Erik J.
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201000843
Subject(s) - hydroxamic acid , chemistry , oxygen atom , variety (cybernetics) , combinatorial chemistry , metal , organic chemistry , stereochemistry , computer science , molecule , artificial intelligence
One dioxygenation please, hold the metal : In the presence of either oxygen or air as the sole oxidant and external oxygen atom source, a variety of unsaturated hydroxamic acids afford cyclic hydroxamates that are readily converted into 1,2‐diols, with the potential for high levels of reaction stereocontrol.