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BioMOFs: Metal–Organic Frameworks for Biological and Medical Applications
Author(s) -
McKinlay Alistair C.,
Morris Russell E.,
Horcajada Patricia,
Férey Gérard,
Gref Ruxandra,
Couvreur Patrick,
Serre Christian
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201000048
Subject(s) - metal organic framework , nanotechnology , computer science , biochemical engineering , materials science , chemistry , engineering , organic chemistry , adsorption
The class of highly porous materials called metal–organic frameworks offer many opportunities for applications across biology and medicine. Their wide range of chemical composition makes toxicologically acceptable formulation possible, and their high level of functionality enables possible applications as imaging agents and as delivery vehicles for therapeutic agents. The challenges in the area encompass not only the development of new solids but also improvements in the formulation and processing of the materials, including tailoring the morphology and surface chemistry of the frameworks to fit the proposed applications.