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The Fundamental Role of Exchange‐Enhanced Reactivity in CH Activation by S =2 Oxo Iron(IV) Complexes
Author(s) -
Janardanan Deepa,
Wang Yong,
Schyman Patric,
Que Lawrence,
Shaik Sason
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201000004
Subject(s) - hebrew , chemistry , quantum chemistry , library science , classics , history , organic chemistry , computer science , reaction mechanism , catalysis
High five : H‐abstraction reactivity by oxo iron(IV) complexes with a quintet ground state is greatly enhanced by exchange stabilization arising from the increased number of d–d exchange interactions near the transition state (see picture). It is postulated that nonheme enzymes evolved to make use of this fundamental mechanism in activation of strong CH bonds.