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Inside Cover: Addition Reactions of Sulfonylimidates with Imines Catalyzed by Alkaline Earth Metals (Angew. Chem. Int. Ed. 32/2009)
Author(s) -
Van Nguyen Huy,
Matsubara Ryosuke,
Kobayashi Shū
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200990165
Subject(s) - alkoxide , catalysis , alkaline earth metal , chemistry , metal , alkali metal , selectivity , int , inorganic chemistry , polymer chemistry , earth (classical element) , organic chemistry , physics , computer science , mathematical physics , operating system
Addition reactions of sulfonylimidates to imines have been successfully catalyzed by alkali earth metal alkoxide salts, which are abundant, inexpensive, and nontoxic. As S. Kobayashi et al. show in their Communication on page 5927 ff., diastereoselectivity is highly dependent on solvents and catalysts: Reactions in DMF proceed with anti selectivity regardless of whether 1,8‐diazabicyclo[5.4.0]undec‐7‐ene or a metal alkoxide is used as catalyst. In THF, syn products can be obtained using a metal alkoxide.