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Cover Picture: Total Synthesis and Absolute Configuration of the Bisanthraquinone Antibiotic BE‐43472B (Angew. Chem. Int. Ed. 19/2009)
Author(s) -
Nicolaou K. C.,
Lim Yee Hwee,
Becker Jochen
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200990095
Subject(s) - courtesy , cover (algebra) , sequence (biology) , total synthesis , stereochemistry , cascade , streptomyces , chemistry , biology , paleontology , philosophy , bacteria , engineering , mechanical engineering , biochemistry , linguistics , chromatography
A cascade sequence featuring a Diels–Alder reaction, a lactolization, and an S N (Ar)‐type substitution forms the core of the bisanthraquinone antibiotic BE‐43472B in its first total synthesis, which K. C. Nicolaou et al. describe in their Communication on page 3444 ff. The background of the cover picture is a photograph of Ecteinascidia turbinata (courtesy of John Easley Photography), the marine source of the streptomyces strain producing this antibiotic.A cascade sequence featuring a Diels–Alder reaction, a lactolization, and an S N (Ar)‐type substitution forms the core of the bisanthraquinone antibiotic BE‐43472B in its first total synthesis, which K. C. Nicolaou et al. describe in their Communication on page 3444 ff. The background of the cover picture is a photograph of Ecteinascidia turbinata (courtesy of John Easley Photography), the marine source of the streptomyces strain producing this antibiotic.