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Enantioselective Kita Oxidative Spirolactonization Catalyzed by In Situ Generated Chiral Hypervalent Iodine(III) Species
Author(s) -
Uyanik Muhammet,
Yasui Takeshi,
Ishihara Kazuaki
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200907352
Subject(s) - hypervalent molecule , enantioselective synthesis , catalysis , substrate (aquarium) , combinatorial chemistry , chemistry , iodine , organic chemistry , biology , ecology
The iodines(III) have it : The rational design of a conformationally flexible C 2 ‐symmetric iodosylarene catalyst has been used for the enantioselective Kita oxidative spirolactonization. The reaction occurs through secondary n–σ* or hydrogen‐bonding interactions between the chiral catalyst and the substrate. Mes=mesityl (2,4,6‐trimethylphenyl).