Premium
Nickel‐Catalyzed Amination of Aryl Pivalates by the Cleavage of Aryl CO Bonds
Author(s) -
Shimasaki Toshiaki,
Tobisu Mamoru,
Chatani Naoto
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200907287
Subject(s) - amination , aryl , chemistry , catalysis , carbene , electrophilic amination , cleavage (geology) , bond cleavage , nickel , electrophile , organic chemistry , medicinal chemistry , combinatorial chemistry , materials science , alkyl , fracture (geology) , composite material
Catalytic amination : The title reaction demonstrates the use of aryl carboxylates as suitable electrophilic coupling substrates in catalytic amination reactions. N‐heterocyclic carbene ligands and NaO t Bu promote the amination of aryl pivalates through the cleavage of normally unreactive aryl carbon–oxygen bonds (see scheme; cod=cyclooctadiene).