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Total Synthesis of Palau’amine
Author(s) -
Seiple Ian B.,
Su Shun,
Young Ian S.,
Lewis Chad A.,
Yamaguchi Junichiro,
Baran Phil S.
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200907112
Subject(s) - history
Worth the wait : The long anticipated total synthesis of palau'amine has been accomplished by a route featuring highly chemoselective transformations, cascade reactions, and a remarkable transannular cyclization to secure the unprecedented trans ‐5,5 ring junction (shown in red).