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Nickel‐Catalyzed Direct CH Arylation and Alkenylation of Heteroarenes with Organosilicon Reagents
Author(s) -
Hachiya Hitoshi,
Hirano Koji,
Satoh Tetsuya,
Miura Masahiro
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200906996
Subject(s) - organosilicon , catalysis , aryl , reagent , nickel , chemistry , surface modification , combinatorial chemistry , polymer chemistry , organic chemistry , alkyl
Breaking the Si‐lence : The direct cross‐coupling of heteroarenes with aryl‐ or alkenylsilanes proceeds efficiently, in the presence of a nickel catalyst, to create a wide range of aryl–and alkenyl–heteroaryl bonds efficiently (see scheme; DMAc= N , N ‐dimethylacetamide, bpy=2,2′‐bipyridine). This catalysis represents a new avenue for using organosilanes in the catalytic CH functionalization chemistry.