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Elucidation of Peptide Effects that Control the Activity of Nanoparticles
Author(s) -
Coppage Ryan,
Slocik Joseph M.,
Sethi Manish,
Pacardo Dennis B.,
Naik Rajesh R.,
Knecht Marc R.
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200906949
Subject(s) - peptide , sequence (biology) , histidine , computational biology , computer science , chemistry , nanotechnology , combinatorial chemistry , biochemistry , biology , materials science , amino acid
A lot of pep : Simple changes to the sequence of peptide nanostructures were found to maintain stability and enhance the activity of peptide‐based palladium nanocatalysts. A histidine to alanine substitution in the peptide chain afforded an increase in turnover frequency from 2234 to 5224, which suggests that the peptide modulates the functionality of bio‐inspired nanomaterials.