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Self‐Assembled TiO 2 Nanocrystal Clusters for Selective Enrichment of Intact Phosphorylated Proteins
Author(s) -
Lu Zhenda,
Ye Miaomiao,
Li Ni,
Zhong Wenwan,
Yin Yadong
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200906648
Subject(s) - nanocrystal , calcination , mesoporous material , nanotechnology , phosphorylation , oxide , chemistry , self assembly , materials science , computer science , computational biology , biochemistry , biology , organic chemistry , catalysis
Mesoporous traps : The title clusters were fabricated through self‐assembly of nanocrystals in emulsion droplets and subsequent protective calcination. The specific affinity offered by the metal oxide and the size‐exclusion mechanism enabled by the mesoporous structure enable the use of these clusters for efficient enrichment of intact phosphorylated proteins from complex biological samples (see picture).