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Reading the Code of Single RNA Molecules
Author(s) -
Müller Sabine
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200906336
Subject(s) - rna , computational biology , transcriptome , population , complementary dna , biology , genetics , gene , gene expression , demography , sociology
Direct RNA sequencing (DRS) is based on the principle of single‐molecule sequencing by synthesis. This next‐generation sequencing technology requires only minute amounts of RNA and has the potential to make snapshots of the transcriptome of any given cell population without the need for copying to cDNA.