Premium
Amplification of Chirality in Monodisperse, Enantiopure Alleno‐Acetylenic Oligomers
Author(s) -
RiveraFuentes Pablo,
AlonsoGómez José Lorenzo,
Petrovic Ana G.,
Santoro Fabrizio,
Harada Nobuyuki,
Berova Nina,
Diederich François
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200906191
Subject(s) - enantiopure drug , chirality (physics) , dispersity , palladium , chemistry , axial chirality , quantum chemical , polymer chemistry , materials science , crystallography , organic chemistry , molecule , physics , catalysis , enantioselective synthesis , chiral symmetry , quantum mechanics , quark , nambu–jona lasinio model
Enantiomerically pure alleno‐acetylenic oligomers of defined lengths were synthesized by the palladium‐mediated oxidative homocoupling of optically pure 1,3‐diethynylallenes. The large amplification of their chiroptical properties strongly suggests the formation of helical secondary structures. This assignment is supported by time‐dependent quantum chemical calculations.