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2D TR‐NOESY Experiments Interrogate and Rank Ligand–Receptor Interactions in Living Human Cancer Cells
Author(s) -
Mari Silvia,
Invernizzi Chiara,
Spitaleri Andrea,
Alberici Luca,
Ghitti Michela,
Bordig Claudio,
Traversari Catia,
Rizzardi GianPaolo,
Musco Giovanna
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200905941
Subject(s) - ranking (information retrieval) , rank (graph theory) , ligand (biochemistry) , information retrieval , cancer , computational biology , two dimensional nuclear magnetic resonance spectroscopy , computer science , receptor , biology , chemistry , mathematics , stereochemistry , combinatorics , genetics
Cell mates : Various ligand–receptor interactions in different human cancer cell lines were probed directly by two‐dimensional transferred‐NOE spectroscopy (see picture) to prove recognition specificity and determine an affinity ranking of several ligands.

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