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Efficient Synthesis of Aryl Fluorides
Author(s) -
Anbarasan Pazhamalai,
Neumann Helfried,
Beller Matthias
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200905855
Subject(s) - aryl , electrophile , tetrahydrofuran , fluoride , chemistry , reagent , combinatorial chemistry , electrophilic addition , organic chemistry , catalysis , alkyl , inorganic chemistry , solvent
Creating CF bonds : A novel electrophilic fluorination of aryl and heteroaryl Grignard reagents has been discovered and was used for the efficient synthesis of various aryl fluoride derivatives (see picture; THF=tetrahydrofuran).
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