Premium
Inside Cover: Protein Scaffold Engineering Towards Tunable Surface Attachment (Angew. Chem. Int. Ed. 49/2009)
Author(s) -
Heyman Ar,
Medalsy Izhar,
Bet Or Oron,
Dgany Or,
Gottlieb Maya,
Porath Danny,
Shoseyov Oded
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200905760
Subject(s) - cover (algebra) , protein engineering , scaffold protein , scaffold , int , chemistry , nanotechnology , materials science , biophysics , computer science , engineering , biochemistry , biomedical engineering , biology , mechanical engineering , signal transduction , enzyme , operating system
Protein engineering holds the key to control, predict, and manipulate bio‐inspired scaffolds on specific surfaces. In their Communication on page 9290 ff., D. Porath, O. Shoseyov, and co‐workers describe selective, controlled, and tunable attachment of proteins to metal or insulating surfaces. SP1, a recently discovered ring‐shaped protein, was genetically engineered to expose multiple binding sites simply by changing solvent conditions. Protein monolayers are created with no need for surface modifications.