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An Aptamer Cross‐Linked Hydrogel as a Colorimetric Platform for Visual Detection
Author(s) -
Zhu Zhi,
Wu Cuichen,
Liu Haipeng,
Zou Yuan,
Zhang Xiaoling,
Kang Huaizhi,
Yang Chaoyong James,
Tan Weihong
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200905570
Subject(s) - biosensor , self healing hydrogels , aptamer , nanotechnology , materials science , polymer , colloidal gold , reagent , computer science , chemistry , nanoparticle , polymer chemistry , biology , genetics , composite material
Cocaine cracked : The gel–sol transition of an enzyme‐caged hydrogel has been efficiently controlled by target binding events, which trigger release of the enzyme to take part in its catalytic role for signal amplification (see picture). As low as 20 ng of cocaine can be visually detected within 10 min without any aid of sophisticated instrumentation.