Histology by Mass Spectrometry: Label‐Free Tissue Characterization Obtained from High‐Accuracy Bioanalytical Imaging | Zendy

Römpp Andreas | Zendy; Guenther Sabine | Zendy; Schober Yvonne | Zendy; Schulz Oliver | Zendy; Takats Zoltan | Zendy; Kummer Wolfgang | Zendy; Spengler Bernhard | Zendy

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Histology by Mass Spectrometry: Label‐Free Tissue Characterization Obtained from High‐Accuracy Bioanalytical Imaging

Author(s) -

Römpp Andreas,

Guenther Sabine,

Schober Yvonne,

Schulz Oliver,

Takats Zoltan,

Kummer Wolfgang,

Spengler Bernhard

Publication year - 2010

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200905559

Subject(s) - characterization (materials science) , computer science , bioanalysis , information retrieval , mass spectrometry imaging , mass spectrometry , medical physics , computational biology , chemistry , nanotechnology , medicine , materials science , biology , chromatography

Next‐generation imaging mass spectrometry of biological tissue on the cellular level shows excellent agreement with histochemical evaluation whilst providing a much higher discrimination capacity based on label‐free molecular information (see image of a mouse urinary bladder section).

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