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Palladium‐Catalyzed Coupling Reactions of Thioimidate N‐Oxides: Access to α‐Alkenyl‐ and α‐Aryl‐Functionalized Cyclic Nitrones
Author(s) -
Schleiss Julie,
Rollin Patrick,
Tatibouët Arnaud
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200905188
Subject(s) - aryl , palladium , scope (computer science) , catalysis , combinatorial chemistry , function (biology) , chemistry , coupling reaction , scheme (mathematics) , computer science , organic chemistry , mathematics , programming language , alkyl , mathematical analysis , evolutionary biology , biology
Surprisingly useful are thioimidate N‐oxides in the preparation of aryl‐ and vinyl‐substituted cyclic ketonitrones through the Liebeskind–Srogl reaction. This novel synthetic approach appears to be efficient and have a broad scope (see scheme).