Highly Stereoselective Synthesis of Monofluoroalkenes from α‐Fluorosulfoximines and Nitrones

A fine fusion : α‐fluorosulfoximines readily react with simple nitrones to give monofluoroalkenes with excellent E / Z stereocontrol (see scheme). This novel fluoroolefination method shows promising applications in medicinal chemistry as monofluoroalkenes are potential mimetics for peptide units as protein inhibitors.