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Evolution of DNA Origami
Author(s) -
Somoza Álvaro
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200904802
Subject(s) - dna origami , schematic , holliday junction , folding (dsp implementation) , dna , nanotechnology , materials science , engineering , biology , mechanical engineering , homologous recombination , genetics , electronic engineering
DNA folding as an extended art form : Long strands of DNA can be folded in a controlled manner to yield 3D shapes. Moreover, twisted and curved shapes can be created with excellent control (see schematic representation). The key to these developments is the use of Holliday junctions, which connect different parts of the array and also create tension in the honeycomb system so that the DNA structure is forced to fold into the desired shape.