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A Convenient and General Iron‐Catalyzed Reduction of Amides to Amines
Author(s) -
Zhou Shaolin,
Junge Kathrin,
Addis Daniele,
Das Shoubhik,
Beller Matthias
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200904677
Subject(s) - reduction (mathematics) , scheme (mathematics) , catalysis , chemistry , computer science , combinatorial chemistry , organic chemistry , mathematics , mathematical analysis , geometry
While the iron is hot : The first general and efficient iron‐catalyzed reduction of secondary and tertiary amides into amines using polymethylhydrosiloxane (PMHS) has been developed (see scheme).