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Multi‐Frequency PARACEST Agents Based on Europium(III)‐DOTA‐Tetraamide Ligands
Author(s) -
Viswanathan Subha,
Ratnakar S. James,
Green Kayla N.,
Kovacs Zoltan,
De LeónRodríguez Luis M.,
Sherry A. Dean
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200904649
Subject(s) - europium , palette (painting) , dota , lanthanide , paramagnetism , chemistry , combinatorial chemistry , computer science , physics , organic chemistry , chelation , ion , quantum mechanics , operating system
Colorful palette : A new class of highly selective Eu 3+ ‐based multi‐frequency PARACEST agents is reported. The complexes can be tuned when administered simultaneously thereby allowing for the possibility of monitoring multiple biomarkers in parallel. PARACEST = paramagnetic chemical exchange saturation transfer.