Multi‐Frequency PARACEST Agents Based on Europium(III)‐DOTA‐Tetraamide Ligands | Zendy

Viswanathan Subha | Zendy; Ratnakar S. James | Zendy; Green Kayla N. | Zendy; Kovacs Zoltan | Zendy; De LeónRodríguez Luis M. | Zendy; Sherry A. Dean | Zendy

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Multi‐Frequency PARACEST Agents Based on Europium(III)‐DOTA‐Tetraamide Ligands

Author(s) -

Viswanathan Subha,

Ratnakar S. James,

Green Kayla N.,

Kovacs Zoltan,

De LeónRodríguez Luis M.,

Sherry A. Dean

Publication year - 2009

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200904649

Subject(s) - europium , palette (painting) , dota , lanthanide , paramagnetism , chemistry , combinatorial chemistry , computer science , physics , organic chemistry , chelation , ion , quantum mechanics , operating system

Colorful palette : A new class of highly selective Eu 3+ ‐based multi‐frequency PARACEST agents is reported. The complexes can be tuned when administered simultaneously thereby allowing for the possibility of monitoring multiple biomarkers in parallel. PARACEST = paramagnetic chemical exchange saturation transfer.

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