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Once Overlooked, Now Made Visible: ATL Proteins and DNA Repair
Author(s) -
Reißner Thomas,
Schorr Stephanie,
Carell Thomas
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200904042
Subject(s) - nucleotide excision repair , dna repair , dna , duplex (building) , chemistry , computational biology , microbiology and biotechnology , biology , biochemistry
Damage report : Alkyltransferase‐like proteins (ATLs) flip DNA lesions out of the DNA duplex but have no catalytic function. They act as recognition proteins that mark DNA lesions and allow repair (see picture; NER=nucleotide excision repair).
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