Premium
Selective Amine Cross‐Coupling Using Iridium‐Catalyzed “Borrowing Hydrogen” Methodology
Author(s) -
Saidi Ourida,
Blacker A. John,
Farah Mohamed M.,
Marsden Stephen P.,
Williams Jonathan M. J.
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200904028
Subject(s) - amine gas treating , isopropyl , iridium , catalysis , alkylation , chemistry , primary (astronomy) , base (topology) , coupling (piping) , hydrogen , combinatorial chemistry , polymer chemistry , organic chemistry , medicinal chemistry , materials science , mathematical analysis , physics , mathematics , astronomy , metallurgy
Something borrowed : Amine cross‐coupling reactions are catalyzed using [{Cp*IrI 2 } 2 ] (Cp*=C 5 Me 5 ) in the absence of a base. A range of anilines were converted into their N ‐isopropyl derivatives, and the same process was also effective for alkylation of benzylamines and other aliphatic primary amines.