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Synthesis of Chiral Tetrasubstituted Alkenes by an Asymmetric Cascade Reaction Catalyzed Cooperatively by Cationic Rhodium(I) and Silver(I) Complexes
Author(s) -
Hojo Daiki,
Noguchi Keiichi,
Tanaka Ken
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200904024
Subject(s) - cationic polymerization , rhodium , cascade , chirality (physics) , chemistry , catalysis , enantioselective synthesis , combinatorial chemistry , scheme (mathematics) , cascade reaction , transformation (genetics) , stereochemistry , organic chemistry , physics , mathematics , particle physics , chiral symmetry breaking , chromatography , nambu–jona lasinio model , quark , mathematical analysis , biochemistry , gene
Fantastic four : Tetrasubstituted alkenes have been prepared with high enantioselectivity by the title transformation. This reaction was successfully applied to the enantio‐ and diastereoselective synthesis of tetrasubstituted helical alkenes possessing both central and helical chirality (see scheme).