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Highly Enantioselective Epoxidation of Styrenes Catalyzed by Proline‐Derived C 1 ‐Symmetric Titanium(Salan) Complexes
Author(s) -
Matsumoto Kazuhiro,
Oguma Takuya,
Katsuki Tsutomu
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200903567
Subject(s) - hydrogen peroxide , enantioselective synthesis , catalysis , styrene , titanium , proline , chemistry , enantiomer , aqueous solution , aqueous medium , organic chemistry , amino acid , copolymer , biochemistry , polymer
Titanium tough! Novel proline‐derived C 1 ‐symmetric titanium(salan) complexes have been used to catalyze the epoxidation of styrene derivatives with aqueous hydrogen peroxide as the oxidant (see scheme). High enantiomeric excesses ranging from 96 to 98 % were obtained.
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