Tumor‐Associated MUC1 Tandem‐Repeat Glycopeptide Microarrays to Evaluate Serum– and Monoclonal–Antibody Specificity | Zendy

Westerlind Ulrika | Zendy; Schröder Hendrik | Zendy; Hobel Alexandra | Zendy; Gaidzik Nikola | Zendy; Kaiser Anton | Zendy; Niemeyer Christof M. | Zendy; Schmitt Edgar | Zendy; Waldmann Herbert | Zendy; Kunz Horst | Zendy

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Tumor‐Associated MUC1 Tandem‐Repeat Glycopeptide Microarrays to Evaluate Serum– and Monoclonal–Antibody Specificity

Author(s) -

Westerlind Ulrika,

Schröder Hendrik,

Hobel Alexandra,

Gaidzik Nikola,

Kaiser Anton,

Niemeyer Christof M.,

Schmitt Edgar,

Waldmann Herbert,

Kunz Horst

Publication year - 2009

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200902963

Subject(s) - muc1 , glycopeptide , monoclonal antibody , tandem repeat , mucin , computational biology , antibody , dna microarray , glycoprotein , microbiology and biotechnology , biology , immunology , genetics , genome , biochemistry , gene , gene expression , antibiotics

Sugar coated diagnosis : A microarray of mucin sialyl‐T N and T N ‐tandem‐repeat glycopeptides was developed (see picture) and used to study the specificity of serum antibodies raised by immunization of mice with synthetic cancer vaccines.

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