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Patterning Mammalian Cells for Modeling Three Types of Naturally Occurring Cell–Cell Interactions
Author(s) -
Chen Zhenling,
Li Yong,
Liu Wenwen,
Zhang Dongzhou,
Zhao Yuyun,
Yuan Bo,
Jiang Xingyu
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200902708
Subject(s) - adhesion , fibronectin , monolayer , cell , cell adhesion , nanotechnology , substrate (aquarium) , cell type , chemistry , computer science , computational biology , materials science , biology , biochemistry , ecology , organic chemistry
Types of stripes : Microfluidic techniques are combined with surface chemistry to pattern multiple types of cells on the same substrate to simulate three types of naturally occurring cell–cell interactions. PDMS=poly(dimethylsiloxane) stamp, FN=fibronectin to promote cell adhesion, SAM=self‐assembled monolayer of an applied alkanethiol that resists cell adhesion.