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Pure Samples of Individual Conformers: The Separation of Stereoisomers of Complex Molecules Using Electric Fields
Author(s) -
Filsinger Frank,
Küpper Jochen,
Meijer Gerard,
Hansen Jonas L.,
Maurer Jochen,
Nielsen Jens H.,
Holmegaard Lotte,
Stapelfeldt Henrik
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200902650
Subject(s) - dipole , electric field , electric dipole moment , conformational isomerism , moment (physics) , bond dipole moment , molecule , separation (statistics) , chemistry , chemical physics , computational chemistry , analytical chemistry (journal) , physics , chromatography , organic chemistry , mathematics , classical mechanics , quantum mechanics , statistics
Keep 'em separated : Stereoisomers of complex molecules generally have very different electric dipole moments for the same mass. The different dipole‐moment‐to‐mass ratios can be exploited in the separation of these species using electric fields. The pure samples thus created offer opportunities in isomer‐specific and stereoselective investigations.