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Ring‐Opening Polymerization with Synergistic Co‐monomers: Access to a Boronate‐Functionalized Polymeric Monolith for the Specific Capture of cis ‐Diol‐Containing Biomolecules under Neutral Conditions
Author(s) -
Ren Lianbing,
Liu Zhen,
Liu Yunchun,
Dou Peng,
Chen HongYuan
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200902469
Subject(s) - monolith , monomer , diol , chemistry , biomolecule , polymerization , amine gas treating , polymer chemistry , protonation , ligand (biochemistry) , combinatorial chemistry , organic chemistry , polymer , catalysis , ion , biochemistry , receptor
Molecular teamwork : Synergistic co‐monomers contained in a boronate‐functionalized polymeric monolith function as a single Wulff‐type boronic acid ligand to enable the specific capture of cis ‐diol‐containing biomolecules under neutral conditions (see scheme). When the medium is made more acidic, the amine group is protonated, and B–N coordination is broken, which results in the release of the cis diol from the monolith.