Premium
Palladium‐Catalyzed Domino Direct Arylation/N‐Arylation: Convenient Synthesis of Phenanthridines
Author(s) -
Candito David A.,
Lautens Mark
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200902400
Subject(s) - phenanthridine , domino , palladium , catalysis , chemistry , combinatorial chemistry , cascade reaction , trimethylsilyl , domino effect , organic chemistry , physics , nuclear physics
Domino reactions possess the ability to generate complexity from simple starting materials. Disclosed is a strategy for the domino direct arylation/N‐arylation for the facile construction of diverse phenanthridine derivatives (see scheme; TMS=trimethylsilyl, TBDMS= tert ‐butyldimethylsilyl).
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom